Spring is the perfect season to refresh and revive your skin, and as an experienced aesthetic nurse prescriber, I’m seeing some exciting advancements that are transforming the way we approach skin rejuvenation. While the days get lighter and the layers come off, it’s time to prioritise skin health and radiance.
This season, three standout trends are taking centre stage in the aesthetic world: Polynucleotides, Profhilo, and Exosomes. Each offers a unique approach to skin regeneration, and when used correctly, they can help clients achieve that glowing, fresh-faced look we all crave as we step into spring.
1. Polynucleotides: The Next Generation of Skin Healing
Polynucleotides are quickly becoming the go-to for deep skin repair and regeneration. Derived from salmon DNA (yes, really!), these powerful biostimulators work by encouraging cellular repair and reducing inflammation. They’re ideal for clients struggling with dull, tired, or stressed skin—especially after winter’s harsh effects.
Why it’s trending:
Unlike dermal fillers that add volume, polynucleotides focus on skin quality. They improve elasticity, hydration, and texture from the inside out. Results are natural, gradual, and beautifully dewy—perfect for clients who want to look refreshed without looking “done.”
My tip:
It is excellent for under-eye rejuvenation, fine lines, and even acne scarring. I love combining polynucleotides with microneedling for a double hit of collagen stimulation.
2. Profhilo: The OG of Injectable Hydration
For good reason, Profhilo continues to hold its ground as a must-have treatment each spring. It’s a unique hyaluronic acid injectable that spreads smoothly under the skin, delivering a surge of hydration while stimulating collagen and elastin.
Why it’s trending:
Spring skin often needs a boost after the dryness of winter, and Profhilo delivers exactly that—without altering facial structure. Think of it as an injectable glow-up: skin looks smoother, tighter, and significantly more hydrated.
My tip:
For optimal results, plan for two sessions four weeks apart. Clients usually start noticing a lit-from-within glow around week three. It pairs beautifully with light treatments like LED or superficial peels.
3. Exosomes: The Cutting-Edge of Cellular Repair
Exosomes are tiny extracellular vesicles that play a massive role in cell communication and regeneration. Originally used in medical treatments, they’ve now entered the aesthetics space as potent rejuvenators that help reduce inflammation, improve skin tone, and speed up recovery.
Why it’s trending:
Clients want results with minimal downtime. Exosomes can be applied post-laser, microneedling, or radiofrequency treatments to enhance healing and amplify collagen production. They’re rich in growth factors and cytokines, making them ideal for tackling fine lines, pigmentation, and overall skin vitality.
My tip:
I’ve had brilliant results using exosomes post-microneedling—clients heal faster, redness disappears quickly, and the skin looks visibly calmer and brighter in just a few days.
Final Thoughts
Spring is all about renewal, and these three treatments are leading the charge when it comes to fresh, healthy skin. Whether you’re looking to deeply hydrate, kickstart collagen, or seriously up your skin regeneration game, there’s a trend here that will fit the bill.
As always, these treatments are only as good as the consultation behind them. Personalised care and professional assessment are key. If you’re thinking of refreshing your skin this season, now’s the perfect time to explore these regenerative powerhouses with a trusted aesthetic professional.
Glow smart, not hard.
Ready to bring your skin back to life this spring? Let’s talk about your goals and create a plan that works for you.
